Talk to your health care provider about birth control methods that may be right for you during this time You should use effective birth control during treatment with PIQRAY and for 1 week after the last dose.Your health care provider will check to see if you are pregnant before you start treatment with PIQRAY.are pregnant or plan to become pregnant.have a history of skin rash, redness of skin, blistering of the lips, eyes or mouth, or skin peeling.Your health care provider may tell you to decrease your dose, temporarily stop your treatment, or completely stop your treatment with PIQRAY if you get certain serious side effects.īefore you take PIQRAY, tell your health care provider about all of your medical conditions, including if you: Your health care provider may tell you to drink more fluids or take medicines to treat diarrhea or colitis Tell your health care provider right away, if you develop diarrhea, stomach-area (abdominal) pain, or see mucus or blood in your stool during treatment with PIQRAY. Severe diarrhea can lead to the loss of too much body water (dehydration) and kidney injury. Diarrhea or colitis (inflammation of your intestines): Diarrhea is common with PIQRAY and may be severe.Lung problems (pneumonitis): Tell your health care provider right away if you develop new or worsening symptoms of lung problems, including shortness of breath or trouble breathing, cough, or chest pain.Tell your health care provider right away if you develop symptoms of hyperglycemia, including excessive thirst, dry mouth, urinating more often than usual or having a higher amount of urine than normal, increased appetite with weight loss, confusion, nausea, vomiting, fruity odor on breath, difficulty breathing, or dry or flushed skin Your health care provider may monitor your blood sugar levels more often if you have a history of type 2 diabetes. Your health care provider will monitor your blood sugar levels before you start and during treatment with PIQRAY. High blood sugar levels (hyperglycemia): Hyperglycemia is common with PIQRAY and may be severe.Severe skin reactions: Tell your health care provider or get medical help right away if you get severe rash or rash that keeps getting worse, reddened skin, flu-like symptoms, blistering of the lips, eyes or mouth, blisters on the skin or skin peeling, with or without fever.Severe allergic reactions: Tell your health care provider or get medical help right away if you have trouble breathing, swelling of the face or throat, flushing, rash, fever, or fast heart rate during treatment with PIQRAY.PIQRAY may cause serious side effects, including: It is not known if PIQRAY is safe and effective in children.ĭo not take PIQRAY if you have had a severe allergic reaction to PIQRAY or are allergic to any of the ingredients in PIQRAY. Your health care provider will test your cancer for an abnormal "PIK3CA" gene to make sure that PIQRAY is right for you. whose disease has progressed on or after endocrine therapy.who have hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer or breast cancer that has spread to other parts of the body (metastatic), with an abnormal phosphatidylinositol-3-kinase catalytic subunit alpha (PIK3CA) gene, and.
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